Title:
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Effect of Puerperal Infections on Early Neonatal Mortality: A
Secondary Analysis of Six Demographic and Health Surveys
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Author:
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Bellizzi, Saverio; Bassat Orellana, Quique; Ali, Mohamed M.; Sobel, Howard L.; Temmerman, Marieen
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Abstract:
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BACKGROUND: Around 1.5 million annual neonatal deaths occur in
the first week of life, and infections represent one of the
major causes in developing countries. Neonatal sepsis is often
strictly connected to infection of the maternal genital tract
during labour. METHODS: The association between signs suggestive
of puerperal infection and early neonatal mortality (<7 days
of life) was performed using Demographic and Health Surveys
(DHS) data of six countries, conducted between 2010 and 2013.
The population attributable fraction (PAF) was generated using
the estimates on early neonatal mortality of a 1990-2013
systematic analysis for the Global Burden of Disease Study.
RESULTS: Signs of puerperal infection ranged from 0.7% in the
Philippines to 16.4% in Honduras. Infection was associated with
a 2.1 adjusted Risk Ratio (95% CI: 1.4-3.2) of early neonatal
mortality. Around five percent of all deaths in the first week
of life were attributable to signs suggestive of puerperal
infections and varied from 13.9% (95% CI: 1.0-26.6) in Honduras
to 3.6% (95% CI: 1.0-8.5) in Indonesia. CONCLUSIONS: Targeted
interventions should be addressed to contain the burden of
puerperal infections on early neonatal mortality. Consideration
of the PAF will help in the discussion of the benefits of
antenatal and perinatal measures. |
Subject(s):
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-Septicèmia -Malalties neonatals -Mortalitat infantil -Septicemia -Neonatal diseases -Infant mortality |
Rights:
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cc by (c) Bellizzi et al., 2017
http://creativecommons.org/licenses/by/3.0/es/ |
Document type:
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Article Article - Published version |
Published by:
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Public Library of Science (PLoS)
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