Títol:
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Streptococcus pneumoniae carriage among healthy and sick
pediatric patients before the generalized implementation of the
13-valent pneumococcal vaccine in Morocco from 2010 to 2011
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Autor/a:
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Jroundi, Imane; Mahraoui, Chafiq; Benmessaoud, Rachid; Moraleda Redecilla, Cinta; Muñoz-Almagro, Carmen; Seffar, M.; Tligui, Houssain; Kettani, Cherif; Benjelloun, Badr Sououd; Alonso, Pedro; Bassat Orellana, Quique
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Abstract:
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Nasopharyngeal carriage studies provide insights into the local
prevalence of circulating pneumococcal serotypes. These data are
critical to vaccination monitoring, as they allow for the
prediction and assessment of impact. Very little data are
available on the carriage of pneumococcal serotypes in Morocco.
Here, we describe the prevalence of Streptococcus pneumoniae
carriage and serotype distribution among 697 pediatric patients
with ages ranging from 2 to 59 months who were admitted to a
Moroccan hospital with severe pneumonia, as well as 195 healthy
infants and young children who were recruited at a vaccination
clinic. Carriage rates were 40.5% (79/195) for healthy children
and 22.8% (159/697) for sick children. The most commonly
observed circulating serotypes included 6A, 6B and 19F, all of
which are included in the current 13-valent anti-pneumococcal
conjugate vaccine that was recently introduced in Morocco.
Monitoring of circulating serotypes remains necessary after
vaccine introduction to assess whether serotype replacement is
occurring. |
Matèries:
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-Pneumococs -Infants -Marroc -Streptococcus pneumonia -Children -Morocco |
Drets:
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cc by-nc-nd (c) Elsevier, 2016
http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
Tipus de document:
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Article Article - Versió acceptada |
Publicat per:
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Elsevier
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