Title:
|
Real-Time Polymerase Chain Reaction in Stool Detects
Transmission of Strongyloides stercoralis from an Infected Donor
to Solid Organ Transplant Recipients
|
Author:
|
Gómez Junyent, Joan; Paredes-Zapata, David; Rodríguez de las Parras, Esperanza; González-Costello, José; Ruiz-Arranz, Ángel; Cañizares, Rosario; Saugar, José María; Muñoz, José
|
Abstract:
|
Solid organ transplant recipients can acquire Strongyloides
stercoralis from an infected donor. The diagnosis of S.
stercoralis in immunocompromised individuals may be challenging
due to a lower sensitivity of available parasitological and
serological methods, compared with immunocompetent individuals.
Recently, a real-time polymerase chain reaction (RT-PCR) in
stool has been developed for S. stercoralis diagnosis. We report
two cases of S. stercoralis infection transmitted by a donor to
two solid organ transplant recipients, whose stool samples were
diagnosed using RT-PCR. This test could play an important role
in S. stercoralis diagnosis in immunosuppressed patients,
facilitating rapid treatment initiation and reducing the risk of
severe strongyloidiasis. Adherence to current recommendations of
screening among donors and recipients from endemic areas is also
urgently needed. |
Subject(s):
|
-Malalties parasitàries -Trasplantament d'òrgans -Parasitic diseases -Transplantation of organs |
Rights:
|
(c) The American Society of Tropical Medicine and Hygiene, 2016
|
Document type:
|
Article Article - Accepted version |
Published by:
|
American Society of Tropical Medicine and Hygiene
|
Share:
|
|