Title:
|
Carriage prevalence of Salmonella enterica serotype Typhi in
gallbladders of adult autopsy cases from Mozambique
|
Author:
|
Lovane, Lucilia; Martínez Yoldi, Miguel Julián; Massora, Sérgio; Mandomando, Inácio; Ussene, Esperança; Jordão, Dercio; Castillo, Paola; Ismail, Mamudo R.; Lorenzoni, Cesaltina; Carrilho, Carla; Bassat Orellana, Quique; Menéndez, Clara; Ordi i Majà, Jaume; Vila Estapé, Jordi; Soto, Sara M. (Sara Maria)
|
Abstract:
|
INTRODUCTION: Typhoid fever is an important public health
problem in many low-income countries where asymptomatic carriers
play an important role in its dissemination. The bacterium
causing typhoid fever can live in the gallstones of asymptomatic
persons after the infection. These carriers are reservoirs of S.
Typhi, are highly contagious, and spread the disease through the
secretion of bacteria in feces and urine. The aim of this study
was to determine the carrier rate in an area of Mozambique.
METHODOLOGY: The presence of S. Typhi was analyzed in
gallbladder samples obtained from 99 adult corpses (in-hospital
deaths) from Mozambique by gold-standard culture and polymerase
chain reaction (PCR). RESULTS: Only one sample was positive with
the culture. However, nine additional samples were positive by
PCR and confirmed by DNA sequencing. Thus, the prevalence of S.
Typhi was 10.1% (10/99). CONCLUSIONS: We report a high
prevalence of S. Typhi in gallbladders among adult autopsy cases
from Mozambique. |
Subject(s):
|
-Salmonel·la -Moçambic -Salmonella -Mozambique |
Rights:
|
cc by (c) Lovane et al., 2016
http://creativecommons.org/licenses/by/3.0/es/ |
Document type:
|
Article Article - Published version |
Published by:
|
The Journal of Infection in Developing Countries
|
Share:
|
|