We give an example showing that, for a nilpotent group $G$ and a set of primes $P$, the $P$-localization homomorphism $l:G \to {G_P}$ need not induce an isomorphism in cohomology with arbitrary (twisted) ${{\mathbf{Z}}_P}$-module coefficients. From this fact we infer that, in the pointed homotopy category of connected CW-complexes, the inclusion of the subcategory of spaces whose higher homotopy groups are ${{\mathbf{Z}}_P}$-modules and whose fundamental group is uniquely ${P'}$-radicable does not admit a left adjoint.