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Título:
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Vitamin D deficiency is associated with the presence and severity of diabetic retinopathy in type 2 Diabetes Mellitus
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Autor/a:
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Alcubierre Calvo, Núria; Valls Marsal, Joan; Rubinat, Esther; Cao, Gonzalo; Esquerda, Aureli; Traveset Maeso, Alicia; Granado Casas, Minerva; Jurjo Campo, Carmen; Mauricio Puente, Dídac
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Notas:
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There is very few evidences on the role of vitamin D in the development of diabetic retinopathy. The aim of the current study was to explore whether there is an association of vitamin D status and diabetic retinopathy in type 2 diabetes. Two groups of patients were selected: 139 and 144 patients with and without retinopathy, respectively, as assessed by an experienced ophthalmologist. Subjects with advanced late diabetic complications were excluded to avoid confounding biases. 25-Hydroxy-vitamin D3 (25(OH)D) concentrations and vitamin D deficiency were associated with the presence of diabetic retinopathy. Additionally, patients with more advanced stages of retinopathy (grades 2
4) had lower concentrations of 25(OH)D and were more frequently vitamin D deficient as compared with patients not carrying this eye complication. In conclusion, our study confirms the association of vitamin D deficiency with the presence and severity of diabetic retinopathy in type 2 diabetes. Further experimental and prospective studies on this issue are clearly warranted.
The authors are grateful to all staff members of the institutions involved in the study that contributed to the recruitment of participants and supported our activities. This study was supported by Grant PS09/01035 from Instituto de Salud Carlos III, Ministry of Economy and Competitiveness, Spain. Nuria Alcubierre holds a predoctoral fellowship also from Instituto de Salud Carlos III FI11/0008. |
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Materia(s):
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-Complicacions de la diabetis
-Malalties de la retina
-Vitamina D
-Diabetes complications
-Retinal diseases
-Vitamin D |
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Derechos:
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cc-by (c) Alcubierre Calvo, Núria et al., 2015
http://creativecommons.org/licenses/by/3.0/es
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Tipo de documento:
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Artículo
Artículo - Versión publicada |
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Editor:
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Hindawi Publishing Corporation
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Compartir:
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